Compile Data Set for Download or QSAR
maximum 50k data
Found 202 of ic50 data for polymerid = 50000949
TargetKinesin-like protein KIF18A(Homo sapiens)
Volastra Therapeutics

US Patent
LigandPNGBDBM636917(N-(5-(4-(6-(4,4-difluoropiperidin-1- yl)pyridin-2-...)
Affinity DataIC50:  1.60nMAssay Description:Test compounds were plated in a 3x dilution scheme in a 384-well plate. Assay buffer: 80 mM PIPES (pH 6.9), 1 mM MgCl2, 75 mM KCl, 1 mM EGTA, 1 mM DT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKinesin-like protein KIF18A(Homo sapiens)
Volastra Therapeutics

US Patent
LigandPNGBDBM636907(N-(4-(4-(5- (cyclopentyl(hydroxy)methyl)furan-2-yl...)
Affinity DataIC50:  2.40nMAssay Description:Test compounds were plated in a 3x dilution scheme in a 384-well plate. Assay buffer: 80 mM PIPES (pH 6.9), 1 mM MgCl2, 75 mM KCl, 1 mM EGTA, 1 mM DT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKinesin-like protein KIF18A(Homo sapiens)
Volastra Therapeutics

US Patent
LigandPNGBDBM637003(N-(4-(4-(6-(4,4-difluoropiperidin-1- yl)pyrazin-2-...)
Affinity DataIC50:  2.80nMAssay Description:Test compounds were plated in a 3x dilution scheme in a 384-well plate. Assay buffer: 80 mM PIPES (pH 6.9), 1 mM MgCl2, 75 mM KCl, 1 mM EGTA, 1 mM DT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKinesin-like protein KIF18A(Homo sapiens)
Volastra Therapeutics

US Patent
LigandPNGBDBM636907(N-(4-(4-(5- (cyclopentyl(hydroxy)methyl)furan-2-yl...)
Affinity DataIC50:  2.80nMAssay Description:Test compounds were plated in a 3x dilution scheme in a 384-well plate. Assay buffer: 80 mM PIPES (pH 6.9), 1 mM MgCl2, 75 mM KCl, 1 mM EGTA, 1 mM DT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKinesin-like protein KIF18A(Homo sapiens)
Volastra Therapeutics

US Patent
LigandPNGBDBM636907(N-(4-(4-(5- (cyclopentyl(hydroxy)methyl)furan-2-yl...)
Affinity DataIC50:  3.10nMAssay Description:Test compounds were plated in a 3x dilution scheme in a 384-well plate. Assay buffer: 80 mM PIPES (pH 6.9), 1 mM MgCl2, 75 mM KCl, 1 mM EGTA, 1 mM DT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKinesin-like protein KIF18A(Homo sapiens)
Volastra Therapeutics

US Patent
LigandPNGBDBM636921(N-(4-(4-(6-(4,4-difluoropiperidin-1- yl)pyrazin-2-...)
Affinity DataIC50:  3.40nMAssay Description:Test compounds were plated in a 3x dilution scheme in a 384-well plate. Assay buffer: 80 mM PIPES (pH 6.9), 1 mM MgCl2, 75 mM KCl, 1 mM EGTA, 1 mM DT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKinesin-like protein KIF18A(Homo sapiens)
Volastra Therapeutics

US Patent
LigandPNGBDBM637019(2-(4,4-difluoropiperidin-1-yl)-6-(1-(4-((2- hydrox...)
Affinity DataIC50:  3.80nMAssay Description:Test compounds were plated in a 3x dilution scheme in a 384-well plate. Assay buffer: 80 mM PIPES (pH 6.9), 1 mM MgCl2, 75 mM KCl, 1 mM EGTA, 1 mM DT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKinesin-like protein KIF18A(Homo sapiens)
Volastra Therapeutics

US Patent
LigandPNGBDBM637005(3-(4,4-difluoropiperidin-1-yl)-5-(1-(4- (ethylsulf...)
Affinity DataIC50:  4.40nMAssay Description:Test compounds were plated in a 3x dilution scheme in a 384-well plate. Assay buffer: 80 mM PIPES (pH 6.9), 1 mM MgCl2, 75 mM KCl, 1 mM EGTA, 1 mM DT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKinesin-like protein KIF18A(Homo sapiens)
Volastra Therapeutics

US Patent
LigandPNGBDBM636954(N-(4-(1-(6-(4,4-difluoropiperidin-1- yl)pyrazin-2-...)
Affinity DataIC50:  4.40nMAssay Description:Test compounds were plated in a 3x dilution scheme in a 384-well plate. Assay buffer: 80 mM PIPES (pH 6.9), 1 mM MgCl2, 75 mM KCl, 1 mM EGTA, 1 mM DT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKinesin-like protein KIF18A(Homo sapiens)
Volastra Therapeutics

US Patent
LigandPNGBDBM637021(N-(4-(4-(2-(4,4-difluoropiperidin-1-yl)-6- (hydrox...)
Affinity DataIC50:  4.40nMAssay Description:Test compounds were plated in a 3x dilution scheme in a 384-well plate. Assay buffer: 80 mM PIPES (pH 6.9), 1 mM MgCl2, 75 mM KCl, 1 mM EGTA, 1 mM DT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKinesin-like protein KIF18A(Homo sapiens)
Volastra Therapeutics

US Patent
LigandPNGBDBM636981(N-(4-(4-(5- (cyclopentyl(hydroxy)methyl)furan-2-yl...)
Affinity DataIC50:  4.60nMAssay Description:Test compounds were plated in a 3x dilution scheme in a 384-well plate. Assay buffer: 80 mM PIPES (pH 6.9), 1 mM MgCl2, 75 mM KCl, 1 mM EGTA, 1 mM DT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKinesin-like protein KIF18A(Homo sapiens)
Volastra Therapeutics

US Patent
LigandPNGBDBM636890(N-(4-(4-(5- (cyclopentyl(hydroxy)methyl)furan-2-yl...)
Affinity DataIC50:  4.70nMAssay Description:Test compounds were plated in a 3x dilution scheme in a 384-well plate. Assay buffer: 80 mM PIPES (pH 6.9), 1 mM MgCl2, 75 mM KCl, 1 mM EGTA, 1 mM DT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKinesin-like protein KIF18A(Homo sapiens)
Volastra Therapeutics

US Patent
LigandPNGBDBM636941(N-(4-(4-(1-(4,4-difluorocyclohexyl)-1H- pyrazol-3-...)
Affinity DataIC50:  5nMAssay Description:Test compounds were plated in a 3x dilution scheme in a 384-well plate. Assay buffer: 80 mM PIPES (pH 6.9), 1 mM MgCl2, 75 mM KCl, 1 mM EGTA, 1 mM DT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKinesin-like protein KIF18A(Homo sapiens)
Volastra Therapeutics

US Patent
LigandPNGBDBM636874(N-(4-(5-(6-(4,4-difluoropiperidin-1- yl)pyridin-2-...)
Affinity DataIC50:  5.10nMAssay Description:Test compounds were plated in a 3x dilution scheme in a 384-well plate. Assay buffer: 80 mM PIPES (pH 6.9), 1 mM MgCl2, 75 mM KCl, 1 mM EGTA, 1 mM DT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKinesin-like protein KIF18A(Homo sapiens)
Volastra Therapeutics

US Patent
LigandPNGBDBM636947(US20230382889, Compound 90a | US20230382889, Compo...)
Affinity DataIC50:  5.20nMAssay Description:Test compounds were plated in a 3x dilution scheme in a 384-well plate. Assay buffer: 80 mM PIPES (pH 6.9), 1 mM MgCl2, 75 mM KCl, 1 mM EGTA, 1 mM DT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKinesin-like protein KIF18A(Homo sapiens)
Volastra Therapeutics

US Patent
LigandPNGBDBM637002(N-(4-(4-(6-(4,4-difluoropiperidin-1- yl)pyrazin-2-...)
Affinity DataIC50:  5.5nMAssay Description:Test compounds were plated in a 3x dilution scheme in a 384-well plate. Assay buffer: 80 mM PIPES (pH 6.9), 1 mM MgCl2, 75 mM KCl, 1 mM EGTA, 1 mM DT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKinesin-like protein KIF18A(Homo sapiens)
Volastra Therapeutics

US Patent
LigandPNGBDBM636947(US20230382889, Compound 90a | US20230382889, Compo...)
Affinity DataIC50:  5.60nMAssay Description:Test compounds were plated in a 3x dilution scheme in a 384-well plate. Assay buffer: 80 mM PIPES (pH 6.9), 1 mM MgCl2, 75 mM KCl, 1 mM EGTA, 1 mM DT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKinesin-like protein KIF18A(Homo sapiens)
Volastra Therapeutics

US Patent
LigandPNGBDBM636927(N-(4-(4-(2-(4,4-difluoropiperidin-1- yl)thiazol-4-...)
Affinity DataIC50:  6nMAssay Description:Test compounds were plated in a 3x dilution scheme in a 384-well plate. Assay buffer: 80 mM PIPES (pH 6.9), 1 mM MgCl2, 75 mM KCl, 1 mM EGTA, 1 mM DT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKinesin-like protein KIF18A(Homo sapiens)
Volastra Therapeutics

US Patent
LigandPNGBDBM637010(N-(4-(4-(6-(cyclpentyloxy)pyrazin-2-yl)- 1H-1,2,3-...)
Affinity DataIC50:  6nMAssay Description:Test compounds were plated in a 3x dilution scheme in a 384-well plate. Assay buffer: 80 mM PIPES (pH 6.9), 1 mM MgCl2, 75 mM KCl, 1 mM EGTA, 1 mM DT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKinesin-like protein KIF18A(Homo sapiens)
Volastra Therapeutics

US Patent
LigandPNGBDBM636996(N-(4-(4-(6-(4,4-difluoropiperidin-1- yl)pyrazin-2-...)
Affinity DataIC50:  6.30nMAssay Description:Test compounds were plated in a 3x dilution scheme in a 384-well plate. Assay buffer: 80 mM PIPES (pH 6.9), 1 mM MgCl2, 75 mM KCl, 1 mM EGTA, 1 mM DT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKinesin-like protein KIF18A(Homo sapiens)
Volastra Therapeutics

US Patent
LigandPNGBDBM636918(N-(4-(4-(6-(3,3-difluoroazetidin-1- yl)pyridin-2-y...)
Affinity DataIC50:  6.5nMAssay Description:Test compounds were plated in a 3x dilution scheme in a 384-well plate. Assay buffer: 80 mM PIPES (pH 6.9), 1 mM MgCl2, 75 mM KCl, 1 mM EGTA, 1 mM DT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKinesin-like protein KIF18A(Homo sapiens)
Volastra Therapeutics

US Patent
LigandPNGBDBM636995(N-(4-(4-(5-fluoro-6-(piperidin-1- yl)pyridin-2-yl)...)
Affinity DataIC50:  6.5nMAssay Description:Test compounds were plated in a 3x dilution scheme in a 384-well plate. Assay buffer: 80 mM PIPES (pH 6.9), 1 mM MgCl2, 75 mM KCl, 1 mM EGTA, 1 mM DT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKinesin-like protein KIF18A(Homo sapiens)
Volastra Therapeutics

US Patent
LigandPNGBDBM636871(N-(4-(5-(6-(4,4-difluoropiperidin-1- yl)pyridin-2-...)
Affinity DataIC50:  6.60nMAssay Description:Test compounds were plated in a 3x dilution scheme in a 384-well plate. Assay buffer: 80 mM PIPES (pH 6.9), 1 mM MgCl2, 75 mM KCl, 1 mM EGTA, 1 mM DT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKinesin-like protein KIF18A(Homo sapiens)
Volastra Therapeutics

US Patent
LigandPNGBDBM636881(N-(4-(4-(6-(4,4-difluoropiperidin-1- yl)pyridin-2-...)
Affinity DataIC50:  6.60nMAssay Description:Test compounds were plated in a 3x dilution scheme in a 384-well plate. Assay buffer: 80 mM PIPES (pH 6.9), 1 mM MgCl2, 75 mM KCl, 1 mM EGTA, 1 mM DT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKinesin-like protein KIF18A(Homo sapiens)
Volastra Therapeutics

US Patent
LigandPNGBDBM636901(N-(4-(4-(6-(4,4-difluoropiperidin-1- yl)pyridin-2-...)
Affinity DataIC50:  6.60nMAssay Description:Test compounds were plated in a 3x dilution scheme in a 384-well plate. Assay buffer: 80 mM PIPES (pH 6.9), 1 mM MgCl2, 75 mM KCl, 1 mM EGTA, 1 mM DT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKinesin-like protein KIF18A(Homo sapiens)
Volastra Therapeutics

US Patent
LigandPNGBDBM636932(N-(3-(azepan-1-yl)-4-(4-(2-(4,4- difluoropiperidin...)
Affinity DataIC50:  7.10nMAssay Description:Test compounds were plated in a 3x dilution scheme in a 384-well plate. Assay buffer: 80 mM PIPES (pH 6.9), 1 mM MgCl2, 75 mM KCl, 1 mM EGTA, 1 mM DT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKinesin-like protein KIF18A(Homo sapiens)
Volastra Therapeutics

US Patent
LigandPNGBDBM637017(N-(4-(4-(5-fluoro-6-(1,2-oxazinan-2- yl)pyridin-2-...)
Affinity DataIC50:  7.10nMAssay Description:Test compounds were plated in a 3x dilution scheme in a 384-well plate. Assay buffer: 80 mM PIPES (pH 6.9), 1 mM MgCl2, 75 mM KCl, 1 mM EGTA, 1 mM DT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKinesin-like protein KIF18A(Homo sapiens)
Volastra Therapeutics

US Patent
LigandPNGBDBM636906(N-(4-(4-(2-(4,4-difluoropiperidin-1- yl)thiazol-4-...)
Affinity DataIC50:  7.20nMAssay Description:Test compounds were plated in a 3x dilution scheme in a 384-well plate. Assay buffer: 80 mM PIPES (pH 6.9), 1 mM MgCl2, 75 mM KCl, 1 mM EGTA, 1 mM DT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKinesin-like protein KIF18A(Homo sapiens)
Volastra Therapeutics

US Patent
LigandPNGBDBM636879(N-(4-(4-(3-((3,3-difluoroazetidin-1- yl)sulfonyl)p...)
Affinity DataIC50:  7.20nMAssay Description:Test compounds were plated in a 3x dilution scheme in a 384-well plate. Assay buffer: 80 mM PIPES (pH 6.9), 1 mM MgCl2, 75 mM KCl, 1 mM EGTA, 1 mM DT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKinesin-like protein KIF18A(Homo sapiens)
Volastra Therapeutics

US Patent
LigandPNGBDBM636982(N-(4-(4-(6-(4,4-difluoropiperidin-1-yl)-5- methylp...)
Affinity DataIC50:  7.30nMAssay Description:Test compounds were plated in a 3x dilution scheme in a 384-well plate. Assay buffer: 80 mM PIPES (pH 6.9), 1 mM MgCl2, 75 mM KCl, 1 mM EGTA, 1 mM DT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKinesin-like protein KIF18A(Homo sapiens)
Volastra Therapeutics

US Patent
LigandPNGBDBM636919(N-(4-(4-(6-(3,3-difluoroazetidin-1- yl)pyridin-2-y...)
Affinity DataIC50:  8nMAssay Description:Test compounds were plated in a 3x dilution scheme in a 384-well plate. Assay buffer: 80 mM PIPES (pH 6.9), 1 mM MgCl2, 75 mM KCl, 1 mM EGTA, 1 mM DT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKinesin-like protein KIF18A(Homo sapiens)
Volastra Therapeutics

US Patent
LigandPNGBDBM636957(N-(4-(4-(2-(3-azabicyclo[3.1.0]hexan-3- yl)-6-meth...)
Affinity DataIC50:  8.10nMAssay Description:Test compounds were plated in a 3x dilution scheme in a 384-well plate. Assay buffer: 80 mM PIPES (pH 6.9), 1 mM MgCl2, 75 mM KCl, 1 mM EGTA, 1 mM DT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKinesin-like protein KIF18A(Homo sapiens)
Volastra Therapeutics

US Patent
LigandPNGBDBM636941(N-(4-(4-(1-(4,4-difluorocyclohexyl)-1H- pyrazol-3-...)
Affinity DataIC50:  8.20nMAssay Description:Test compounds were plated in a 3x dilution scheme in a 384-well plate. Assay buffer: 80 mM PIPES (pH 6.9), 1 mM MgCl2, 75 mM KCl, 1 mM EGTA, 1 mM DT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKinesin-like protein KIF18A(Homo sapiens)
Volastra Therapeutics

US Patent
LigandPNGBDBM636912(N-(4-(4-(6-morpholinopyridin-2-yl)-1H- 1,2,3-triaz...)
Affinity DataIC50:  8.30nMAssay Description:Test compounds were plated in a 3x dilution scheme in a 384-well plate. Assay buffer: 80 mM PIPES (pH 6.9), 1 mM MgCl2, 75 mM KCl, 1 mM EGTA, 1 mM DT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKinesin-like protein KIF18A(Homo sapiens)
Volastra Therapeutics

US Patent
LigandPNGBDBM636991(N-(tert-butyl)-5-(1-(4-(ethylsulfonamido)- 2-(6-az...)
Affinity DataIC50:  8.5nMAssay Description:Test compounds were plated in a 3x dilution scheme in a 384-well plate. Assay buffer: 80 mM PIPES (pH 6.9), 1 mM MgCl2, 75 mM KCl, 1 mM EGTA, 1 mM DT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKinesin-like protein KIF18A(Homo sapiens)
Volastra Therapeutics

US Patent
LigandPNGBDBM636923(N-(4-(1-(3-(4,4-difluoropiperidin-1- yl)phenyl)-1H...)
Affinity DataIC50:  8.60nMAssay Description:Test compounds were plated in a 3x dilution scheme in a 384-well plate. Assay buffer: 80 mM PIPES (pH 6.9), 1 mM MgCl2, 75 mM KCl, 1 mM EGTA, 1 mM DT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKinesin-like protein KIF18A(Homo sapiens)
Volastra Therapeutics

US Patent
LigandPNGBDBM636884(N-(4-(4-(6-(4,4-difluoropiperidin-1- yl)pyridin-2-...)
Affinity DataIC50:  8.70nMAssay Description:Test compounds were plated in a 3x dilution scheme in a 384-well plate. Assay buffer: 80 mM PIPES (pH 6.9), 1 mM MgCl2, 75 mM KCl, 1 mM EGTA, 1 mM DT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKinesin-like protein KIF18A(Homo sapiens)
Volastra Therapeutics

US Patent
LigandPNGBDBM636967(N-(4-(4-(2-(cyclopentyloxy)-6- methylpyrimidin-4-y...)
Affinity DataIC50:  8.80nMAssay Description:Test compounds were plated in a 3x dilution scheme in a 384-well plate. Assay buffer: 80 mM PIPES (pH 6.9), 1 mM MgCl2, 75 mM KCl, 1 mM EGTA, 1 mM DT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKinesin-like protein KIF18A(Homo sapiens)
Volastra Therapeutics

US Patent
LigandPNGBDBM636983(N-(4-(4-(5-(cyclopent-1-en-1-yl)furan-2- yl)-1H-1,...)
Affinity DataIC50:  9nMAssay Description:Test compounds were plated in a 3x dilution scheme in a 384-well plate. Assay buffer: 80 mM PIPES (pH 6.9), 1 mM MgCl2, 75 mM KCl, 1 mM EGTA, 1 mM DT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKinesin-like protein KIF18A(Homo sapiens)
Volastra Therapeutics

US Patent
LigandPNGBDBM636878(N-(tert-butyl)-3-(1-(4- (methylsulfonamido)-2-(6- ...)
Affinity DataIC50:  9.10nMAssay Description:Test compounds were plated in a 3x dilution scheme in a 384-well plate. Assay buffer: 80 mM PIPES (pH 6.9), 1 mM MgCl2, 75 mM KCl, 1 mM EGTA, 1 mM DT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKinesin-like protein KIF18A(Homo sapiens)
Volastra Therapeutics

US Patent
LigandPNGBDBM636902(N-(5-(4-(6-(4,4-difluoropiperidin-1- yl)pyridin-2-...)
Affinity DataIC50:  9.10nMAssay Description:Test compounds were plated in a 3x dilution scheme in a 384-well plate. Assay buffer: 80 mM PIPES (pH 6.9), 1 mM MgCl2, 75 mM KCl, 1 mM EGTA, 1 mM DT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKinesin-like protein KIF18A(Homo sapiens)
Volastra Therapeutics

US Patent
LigandPNGBDBM636876(N-(4-(5-(6-morpholinopyridin-2-yl)-1H- imidazol-2-...)
Affinity DataIC50:  9.20nMAssay Description:Test compounds were plated in a 3x dilution scheme in a 384-well plate. Assay buffer: 80 mM PIPES (pH 6.9), 1 mM MgCl2, 75 mM KCl, 1 mM EGTA, 1 mM DT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKinesin-like protein KIF18A(Homo sapiens)
Volastra Therapeutics

US Patent
LigandPNGBDBM636950(N-(4-(4-(5-(cyclopentanecarbonyl)furan- 2-yl)-1H-1...)
Affinity DataIC50:  9.60nMAssay Description:Test compounds were plated in a 3x dilution scheme in a 384-well plate. Assay buffer: 80 mM PIPES (pH 6.9), 1 mM MgCl2, 75 mM KCl, 1 mM EGTA, 1 mM DT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKinesin-like protein KIF18A(Homo sapiens)
Volastra Therapeutics

US Patent
LigandPNGBDBM636929(N-(4-(1-(6-(4,4-difluoropiperidin-1- yl)pyridin-2-...)
Affinity DataIC50:  10nMAssay Description:Test compounds were plated in a 3x dilution scheme in a 384-well plate. Assay buffer: 80 mM PIPES (pH 6.9), 1 mM MgCl2, 75 mM KCl, 1 mM EGTA, 1 mM DT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKinesin-like protein KIF18A(Homo sapiens)
Volastra Therapeutics

US Patent
LigandPNGBDBM636951(N-(4-(4-(2-(4,4-difluoropiperidin-1-yl)-5- fluorot...)
Affinity DataIC50:  10nMAssay Description:Test compounds were plated in a 3x dilution scheme in a 384-well plate. Assay buffer: 80 mM PIPES (pH 6.9), 1 mM MgCl2, 75 mM KCl, 1 mM EGTA, 1 mM DT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKinesin-like protein KIF18A(Homo sapiens)
Volastra Therapeutics

US Patent
LigandPNGBDBM636940(N-(4-(4-(1-cyclopentyl-1H-pyrazol-3-yl)- 1H-1,2,3-...)
Affinity DataIC50:  10nMAssay Description:Test compounds were plated in a 3x dilution scheme in a 384-well plate. Assay buffer: 80 mM PIPES (pH 6.9), 1 mM MgCl2, 75 mM KCl, 1 mM EGTA, 1 mM DT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKinesin-like protein KIF18A(Homo sapiens)
Volastra Therapeutics

US Patent
LigandPNGBDBM636888(N-(4-(4-(6- (cyclopentyl(hydroxy)methyl)pyridin-2-...)
Affinity DataIC50:  11nMAssay Description:Test compounds were plated in a 3x dilution scheme in a 384-well plate. Assay buffer: 80 mM PIPES (pH 6.9), 1 mM MgCl2, 75 mM KCl, 1 mM EGTA, 1 mM DT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKinesin-like protein KIF18A(Homo sapiens)
Volastra Therapeutics

US Patent
LigandPNGBDBM636889(N-(4-(4-(6-((4,4-difluoropiperidin-1- yl)methyl)py...)
Affinity DataIC50:  11nMAssay Description:Test compounds were plated in a 3x dilution scheme in a 384-well plate. Assay buffer: 80 mM PIPES (pH 6.9), 1 mM MgCl2, 75 mM KCl, 1 mM EGTA, 1 mM DT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKinesin-like protein KIF18A(Homo sapiens)
Volastra Therapeutics

US Patent
LigandPNGBDBM636985(US20230382889, Compound 127A | US20230382889, Comp...)
Affinity DataIC50:  11nMAssay Description:Test compounds were plated in a 3x dilution scheme in a 384-well plate. Assay buffer: 80 mM PIPES (pH 6.9), 1 mM MgCl2, 75 mM KCl, 1 mM EGTA, 1 mM DT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKinesin-like protein KIF18A(Homo sapiens)
Volastra Therapeutics

US Patent
LigandPNGBDBM636942(N-(4-(4-(6-(4,4-difluoropiperidin-1- yl)pyridin-2-...)
Affinity DataIC50:  11nMAssay Description:Test compounds were plated in a 3x dilution scheme in a 384-well plate. Assay buffer: 80 mM PIPES (pH 6.9), 1 mM MgCl2, 75 mM KCl, 1 mM EGTA, 1 mM DT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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